Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2010 1
2013 1
2014 3
2015 1
2016 3
2017 2
2019 3
2020 3
2021 3
2022 2
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

21 results

Results by year

Filters applied: . Clear all
Page 1
VNTR Polymorphism in the Intron 5 of SIRT3 and Susceptibility to Breast Cancer.
Payavula HY, Jamadandu D, Velpula S, Digumarti RR, Satti V, Annamaneni S. Payavula HY, et al. Asian Pac J Cancer Prev. 2023 Mar 1;24(3):859-865. doi: 10.31557/APJCP.2023.24.3.859. Asian Pac J Cancer Prev. 2023. PMID: 36974538 Free PMC article.
Genetic variants or dysregulation of SIRT3 was known to associate with poor prognosis of recurrence and relapse in few cancers. ...Further studies are warranted to study the prognostic and therapeutic significance of this SIRT3 polymorphism....
Genetic variants or dysregulation of SIRT3 was known to associate with poor prognosis of recurrence and relapse in few cancers. ...Fu …
PGC-1alpha activates SIRT3 to modulate cell proliferation and glycolytic metabolism in breast cancer.
Zu Y, Chen XF, Li Q, Zhang ST, Si LN. Zu Y, et al. Neoplasma. 2021 Mar;68(2):352-361. doi: 10.4149/neo_2020_200530N584. Epub 2020 Nov 25. Neoplasma. 2021. PMID: 33231084
Additionally, PGC-1alpha or SIRT3 also induced the inhibition of glycolysis metabolism. Moreover, the expression of SIRT3 was positively regulated by PGC-1alpha. Silencing SIRT3 partly reversed the negative effects of PGC-1alpha on glycolytic metabolism. ...
Additionally, PGC-1alpha or SIRT3 also induced the inhibition of glycolysis metabolism. Moreover, the expression of SIRT3 was …
Polymorphisms in genes involved in breast cancer among Iranian patients.
Farnoosh G, Saeedi-Boroujeni A, Jalali A, Keikhaei B, Mahmoudian-Sani MR. Farnoosh G, et al. Per Med. 2021 Mar;18(2):153-169. doi: 10.2217/pme-2020-0003. Epub 2021 Feb 10. Per Med. 2021. PMID: 33565318 Review.
Several single nucleotide polymorphisms were considered as breast cancer susceptibility polymorphisms within genes (STK15, ERRs, ESR1, p53, SEP15, AURKA, SHBG, SRC, FAS, VEGF, XRCC1, GST, NFkappaB1, XPC, XRCC3, sirtuin-3, NKG2D). Cytosine-adenine repeat (IGF-I), rs3 …
Several single nucleotide polymorphisms were considered as breast cancer susceptibility polymorphisms within genes (STK15, ERRs, ESR1, p53, …
SIRT3-mediated mitochondrial unfolded protein response weakens breast cancer sensitivity to cisplatin.
Chen H, Zhang DM, Zhang ZP, Li MZ, Wu HF. Chen H, et al. Genes Genomics. 2021 Dec;43(12):1433-1444. doi: 10.1007/s13258-021-01145-5. Epub 2021 Aug 2. Genes Genomics. 2021. PMID: 34338986
UPR(mt) inducer Nicotinamide ribose (NR) could promote the proliferation and invasion of breast cancer cells treated with cisplatin. Importantly, SIRT3 was discovered to increase UPR(mt) in breast cancer cells and silencing of SIRT3 could inhibit the effect of NR in …
UPR(mt) inducer Nicotinamide ribose (NR) could promote the proliferation and invasion of breast cancer cells treated with cisplatin. Importa …
Mitohormesis Primes Tumor Invasion and Metastasis.
Kenny TC, Craig AJ, Villanueva A, Germain D. Kenny TC, et al. Cell Rep. 2019 May 21;27(8):2292-2303.e6. doi: 10.1016/j.celrep.2019.04.095. Cell Rep. 2019. PMID: 31116976 Free PMC article.
In this subpopulation, UPR(mt) activation persists in the absence of stress, resulting in reduced oxidative stress indicative of mitohormesis. Mechanistically, we showed that the SIRT3 axis of UPR(mt) is necessary for invasion and metastasis. In breast cancer patients, a 7 …
In this subpopulation, UPR(mt) activation persists in the absence of stress, resulting in reduced oxidative stress indicative of mitohormesi …
Metabolic/hypoxial axis predicts tamoxifen resistance in breast cancer.
Azzam HN, El-Derany MO, Wahdan SA, Faheim RM, Helal GK, El-Demerdash E. Azzam HN, et al. Sci Rep. 2022 Sep 27;12(1):16118. doi: 10.1038/s41598-022-19977-w. Sci Rep. 2022. PMID: 36167713 Free PMC article.
Quantification of plasma LncRNA Taurine upregulated-1 (TUG-1), miRNA 186-5p (miR-186), serum Sirtuin-3 (SIRT3), Peroxisome Proliferator Activator Receptor alpha (PPAR-1 alpha) and Hypoxia Inducible Factor-1 (HIF-1alpha) was done in a cohort of patients divide …
Quantification of plasma LncRNA Taurine upregulated-1 (TUG-1), miRNA 186-5p (miR-186), serum Sirtuin-3 (SIRT3), Peroxis …
Kaempferol and Apigenin suppresses the stemness properties of TNBC cells by modulating Sirtuins.
Sharma A, Sinha S, Keswani H, Shrivastava N. Sharma A, et al. Mol Divers. 2022 Dec;26(6):3225-3240. doi: 10.1007/s11030-022-10384-x. Epub 2022 Feb 7. Mol Divers. 2022. PMID: 35129762
Our mechanistic approach indicated that KMP and API inhibited SIRT3 and SIRT6 proteins, as evidenced by our in silico and in vitro experiment. ...
Our mechanistic approach indicated that KMP and API inhibited SIRT3 and SIRT6 proteins, as evidenced by our in silico and in vitro ex …
High-throughput screening of Sirtuin family of genes in breast cancer.
Igci M, Kalender ME, Borazan E, Bozgeyik I, Bayraktar R, Bozgeyik E, Camci C, Arslan A. Igci M, et al. Gene. 2016 Jul 15;586(1):123-8. doi: 10.1016/j.gene.2016.04.023. Epub 2016 Apr 11. Gene. 2016. PMID: 27080717
Particularly, expressions of SIRT1 and SIRT4 were found to be significantly down-regulated in breast cancer tissues and SKBR3 breast cancer cells. In contrast, SIRT2, SIRT3, and SIRT5 genes were shown to be up-regulated in our study. Although SIRT6 and SIRT7 were also up-r …
Particularly, expressions of SIRT1 and SIRT4 were found to be significantly down-regulated in breast cancer tissues and SKBR3 breast cancer …
Decreased mitochondrial SIRT3 expression is a potential molecular biomarker associated with poor outcome in breast cancer.
Desouki MM, Doubinskaia I, Gius D, Abdulkadir SA. Desouki MM, et al. Hum Pathol. 2014 May;45(5):1071-7. doi: 10.1016/j.humpath.2014.01.004. Epub 2014 Jan 23. Hum Pathol. 2014. PMID: 24746213 Free PMC article.
Genetic deletion of Sirt3 in mice leads to the spontaneous development of mammary tumors starting at 1 year, and decreased SIRT3 messenger RNA has been observed in several human tumors including breast malignancies. In this investigation, we assessed SIRT3 ex …
Genetic deletion of Sirt3 in mice leads to the spontaneous development of mammary tumors starting at 1 year, and decreased SIRT3 …
New Gene Profiling in Determination of Breast Cancer Recurrence and Prognosis in Iranian Women.
Poorhosseini SM, Hashemi M, Alipour Olyaei N, Izadi A, Moslemi E, Ravesh Z, Hashemi-Gorji F, Kheiri HR, Yassaee VR. Poorhosseini SM, et al. Asian Pac J Cancer Prev. 2016;17(S3):155-60. doi: 10.7314/apjcp.2016.17.s3.155. Asian Pac J Cancer Prev. 2016. PMID: 27165221 Free article.
The objective of this study was to examine the gene expression profiles of SIRT3, HRAS, LSP1, SCUBE2 and AP2A2 in Iranian women with BC.A total of 136 patients including healthy controls were categorized into three groups based on the relapse of the disease. ...This study …
The objective of this study was to examine the gene expression profiles of SIRT3, HRAS, LSP1, SCUBE2 and AP2A2 in Iranian women with …
21 results